2
Premarin, the nation's first hormone replacement therapy
medication is put on the market.
1973
A clinical trial of men taking Premarin to prevent heart attacks
and strokes is stopped when it is discovered that the test
subjects were actually having more heart attacks and
blood clots.
1975
Two studies published in the New England Journal of Medicine
indicate that post-menopausal estrogen use increases the risk of
endometrial cancer four to fourteen times.
1976
The first study showing a link between menopausal estrogen use
and breast cancer is published in the New England Journal of
Medicine.
1982
In the journal Cancer Research, several experts say menopausal
hormones are a major factor in cancer.
1985
A Framingham Heart Study report shows 1,234 women taking
estrogen had more cardiovascular events than women who did not
use hormones.
1989
A Swedish study of 23,244 women who had used estrogen or
estrogen plus progestin published in the New England Journal of
Medicine shows a slight increase in breast cancer among those
who took estrogen. Further, when women switched to combination
hormone replacement therapy, their breast cancer risk more than
doubled.
May
31, 2002
The Food & Drug Administration announces it will more carefully
evaluate hormone replacement therapy medications, including
Prempro. This was the first official response by the government
to the National Heart, Lung and Blood Institute (NHLBI) study
that found an increase in serious side effects related to
Prempro.
1990 - 1995
Premarin is the most frequently dispensed drug in the U.S.
1995
Prempro, the first
estrogen-plus-progestin hormone replacement therapy drug is
approved by the FDA.
1998 The first major placebo-controlled trial of HRT shows that
the hormones do not help women who have already had a heart
attack and, in fact, caused more heart attacks, strokes, and
other cardiovascular events.
2000
The Women's Health Initiative tells study participants that some
women are experiencing heart attacks and strokes and offers them
the chance to drop out.
2002 The Women's Health Initiative's combined HRT study is stopped because of
continuing heart events and an increased risk of invasive breast cancer. Doctors
are urged to prescribe HRT only for short-term relief. May 31, 2002
The Data and Safety Monitoring Board reviews data indicating
women who took Prempro suffered a much higher rate of breast cancer.
July 9, 2002
The National Heart, Lung and Blood Institute abruptly halts its
clinical trial intended to evaluate the risks and benefits of Prempro after
preliminary research indicated a significantly higher incidence of severe side
effects. The trial was scheduled to go three more years.
August 13, 2002
The FDA announces it will more carefully evaluate hormone replacement therapy
pharmaceuticals, including Prempro. This was the first official response by the
government to the NHLBI study that found an increase in serious side effects
related to Prempro.
Robert
A. Kraft
Prempro
®
Safety Alert!
Contact Us
Today For a Free Consultation
We are Prempro hormone replacement therapy lawyers. Call us if you or a loved one has
taken Prempro, Premarin, Premphrase, Provera, or other
hormone replacement therapy drugs. You may have an increased
risk of breast cancer, ovarian cancer, endometrial cancer,
stroke, heart attack, or blood clot.
Whatever legal problem you may have, our Prempro
attorneys want to help you. You can see us for free. Please
call us now. You may be entitled to receive compensation for your
injuries.
Our law firm can assist you in making a claim under these circumstances:
Pulmonary embolism, heart attack, stroke, or blood clot
event -- You took hormone therapy replacement drugs for
12 months or less prior to the event. If you took the
drugs for more than 12 months before the event, it is
very difficult to prove the drugs caused the event.
Breast cancer -- You took hormone therapy replacement
drugs for three years or longer before the diagnosis of
cancer, and have positive hormone receptors as part of
the diagnosis. This is referred to as "hormone positive"
cancer.
Other
cancers -- You took hormone therapy replacement drugs
for three years or longer before the diagnosis of
cancer. These hormone-related cancers are normally
limited to ovarian, gall bladder, uterine, and sometimes
other types.
To get more information about the ways we can help you with your
Prempro
claim, click on Submit Your Claim at
the left side of this page, send an
e-mail to info@kraftlaw.com, or just pick
up your phone and call us at (800) 989-9999. There will be absolutely no charge or obligation for a consultation with our
firm.
In The Public Interest: Even if you are not considering making a legal claim for
exposure to hormone replacement therapy drugs, we strongly urge you to contact your
doctor if you have taken these medications. Your doctor will
be able to explain any risk of injury, and
will be able to advise you on the proper medical course of
action.
If you are considering making a legal claim, your rights and
obligations will vary depending on many different factors.
You should act promptly in getting advice from a lawyer so
you will fully understand your rights and be in a better
position to protect them. At Kraft and Associates, we
provide this initial advice without charge or further
obligation.
Please visit the
Legal
Articles and Online Resources
pages at this site for more information about Premarin and
other types of hormone replacement therapy medications.
Kraft &
Associates can help you with any pharmaceutical claim.
Our Texas personal
injury lawyers
can help you if you live anywhere in
Texas, including Dallas, Fort Worth, Houston, Austin, San
Antonio, Abilene, Amarillo, Beaumont, Brownsville, Corpus
Christi, El Paso, Laredo, Lubbock, Midland, Odessa, Texarkana,
Tyler, Waco, Wichita Falls or any other city in Texas. There is
no charge to contact our attorneys for a free evaluation of your
claim.
Kraft & Associates, P.C.
maintains offices in Dallas, Texas. We serve all areas of North Texas,
including Dallas County, Tarrant County, Denton County and the cities of
Dallas, Fort Worth, Arlington, Irving, Grand Prairie, Garland, Mesquite,
Richardson, Plano, Frisco, Carrollton, Farmers Branch, Lewisville, Hurst,
Euless, Bedford, Grapevine, Coppell, Colleyville, Duncanville, DeSoto,
Cedar Hill, Lancaster and Rockwall. We also accept cases throughout Texas,
including
Houston, Austin, San Antonio, Tyler, El Paso, Waco, Lubbock, Amarillo,
Corpus Christi, Brownsville, Beaumont, Abilene, Wichita Falls, Laredo,
Midland, Odessa, Texarkana or any other city in Texas.
Cases may be referred to other attorneys. Prempro is a registered
trademark of Wyeth Pharmaceuticals.
®
Please read this
Legal
Mumbo Jumbo before acting on any information contained in this Web
site.
Click here for a
Map to our office or call us at (214) 999-9999 for driving directions.
All questions concerning this Web page should be directed to
Robert Kraft. The attorney
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Bar Rules is Robert Kraft.
